6th Annual Biomarkers Congress
23rd & 24th February 2011, Hilton Deansgate Hotel, Manchester, UK
6th Annual Biomarkers Congress is administered by Osney Media.
Programme
6th Annual Biomarkers Congress
23rd & 24th February 2011
Wednesday 23rd February 2011 to Thursday 24th February 2011
The Hilton Deansgate Hotel, Manchester, UK, -
£650.00/person

6th ANNUAL BIOMARKERS CONGRESS: the leading event for biomarkers practitioners

 

The pharmaceutical industry is facing high clinical development costs and declining drug discovery success rates. To stay competitive companies are re-evaluating their drug development process to reduce attrition rates. Biomarkers promises to transform drug discovery, clinical development and molecular diagnostics in the R&D process as effective use of biomarkers at each stage of R&D can improve decision-making, increase clinical trial success rates and productivity.

 

The 6th Annual Biomarkers Congress 2011 presented by Oxford Global Conferences provides a first class educational and networking opportunity for over 200 attendees to gain knowledge and insights into the Biomarkers marketplace.

 

The event explores core topics such as discovery & validation strategies, regulatory issues, the key role of personalised medicine and diagnostics, safety biomarkers and biomarkers within clinical development, as well as the integration of applications and enabling technologies such as genomics, microRNA, systems biology to maximise biomarker identification. 

 

Do not miss out on the opportunity to learn how you can streamline your R&D process and identify potential cost savings through successful biomarker discovery, validation and clinical development. Focus on the integration of technologies & applications to bridge the gap between Discovery, Validation and Development.

 

CONFERENCE AGENDA

STREAM TITLES

·          Biomarker Discovery & Validation Strategies & Regulation

·          Companion Diagnostics & Stratified Medicine

·          Safety & Biomarkers in Clinical Development

·          Enabling Technologies to Maximise Biomarker Identification

·          Oncology Biomarkers

 

Day One

Keynote Presentations

From Representatives from FDA and EMA

 

Stream One         Biomarker Discovery & Validation Strategies & Regulation

Regulatory Issues

Validation

IMI Update

Outsourcing Models

Pharmacoeconomics of Biomarkers

Level of Characterisation of Biomarkers Required For Internal Go / No Go Key Investment Decision Making 

 

Stream Two         Companion Diagnostics & Stratified Medicine

Development of Companion Diagnostics including Novel Therapies

Understanding Regulatory aspects Concerning Companion Diagnostics

Case Study Examples

Development Through Predictive v Retrospective Biomarker Analysis

Statistical Issues and Stratified medicine

Challenges in Developing A Clinically Validated Companion Diagnostic

FDA Guidance

 

Day Two

Stream One         Safety & Biomarkers in Clinical Development

Safe-T Consortium Case Study

Safety Biomarker Case Studies

Use of Safety Biomarkers for Guided Drug Development

Use of Predictive Animal Models

Translating Clinical Biomarkers into Clinical Decisions

Developing Molecular Biomarkers to Replace Traditional Clinical Endpoints

 

Stream Two          Enabling Technologies to Maximise Biomarker Identification

Systems Biology Approaches to Inform Clinical Studies

Circulating Messenger RNA

MicroRNA

Epigenetics / DNA Methalytion

Pharmacogenetics

NGS

Multiplexing Technology

Biobanking as an Enabling Technology for Biomarker Research

 

 

Oncology Biomarkers Congress (Day 1 and 2)

Challenges in Oncology Drug Development

 K-RAS Success Story

Oncology Biomarker Case Studies by Disease Area

Diagnostics v Pharmacodynamics

Exploring PK/PD Interactions and Applications

Use Of PK/PD Modelling Approaches to Impact Oncology Drug Development

Utilizing Biomarkers to Support Targeted therapies in Oncology

Use of gene Expression to Deliver Approaches Personalised Cancer Therapy

Selecting the Right Biomarker in Oncology Patients

Patient Selection

Circulating Tumour Cells

Translating In Vitro and Lab findings into Clinical Applications

 

 

Roundtable Discussions

CNS

Respiratory

Cardiovascular, Metabolic and Endocrine Diseases

Oncology

Inflammation

Neurology

 

The conference this year will be co-located with the inaugural Oncology Biomarkers Congress which will also last two days and will give the opportunity to drill down into this particular therapeutic area.

 

The Conference Agenda has been shaped by research with an expert advisory panel:

 

Advisory Panel IncludeS:

·            Francis Kalush, Network Leader for the Diagnostics (In vivo and In Vitro) and Personalized Medicine Network, FDA

·            Alain van Gool, Head Molecular Profiling, Translational Medicine Research Centre, Merck Research Laboratories, MSD, Singapore

·            Neil French, Senior Scientific Operations Manager, MRC Centre for Drug Safety Science, Department of Pharmacology & Therapeutics, The University of Liverpool

·            Mark Jones, Associate Director Molecular Biomarkers, Global Exploratory Development, UCB New Medicines

·            Miro Venturi, Senior Biomarker & Experimental Medicine Leader, Roche Pharma Development

·            Mike Lau, Principal Clinical Development Scientist, GSK Oncology

·            Gary Coulton, Director St. George's Medical Biomics Centre, St. George', University of London

·            Chris Chamberlain, Medical Director Personalised Medicine, AstraZeneca

·            Steve Furlong, Safety Science Lead and Senior Director, AstraZeneca

·            Samila Mihindukulasuriya, Senior. Contract Analyst, Biomarkers, GSK

·            Iain Kilty, Director Allergy & Respiratory Research Unit, Pfizer            

·            Matt Squires, Associate Director Translational Biology, Astex Therapeutics

·            Ian Wilson, Senior Principal Scientist, Dept. of Drug Metabolism and Pharmacokinetics, AstraZeneca

·            Patricia Hurley, Head of Project Management and Biomarkers Division, ERA Consulting (UK) Ltd

·            Samual Murray, President, Greek Society of Molecular Oncology (ElEMO), Professor University of Ioannina Cancer Biobank

·            Michael Shi, Director and Biomarker Project Leader of Exploratory Oncology Development, Novartis

·            Simon Westbrook, Head of in Vivo Pharmacology, Biomarkers, Pfizer

·            Dominic Eisinger, Director of Strategic Development, Rules-Based Medicine, Inc

·            Michael Shi, Director and Biomarker Project Leader of Exploratory Oncology Development, Novartis

·            Simon Westbrook, Head of in Vivo Pharmacology, Biomarkers, Pfizer

·            Dominic Eisinger, Director of Strategic Development, Rules-Based Medicine, Inc

 

 

Delegates will benefit from:

- An executive format providing intimate interaction with industry peers’ ideas and experiences through case study presentations and panel discussions

- Networking opportunities and sharing ideas with other senior biomarker practitioners

- Pre-scheduled one-to-one meetings between you and solution providers will provide you with an opportunity to forge partnerships and discover solutions

- Post event follow up offering all documentation from the meeting and re-booking discounts

- Tailor-made agenda – hand pick any conference and panel sessions you wish to attend

 

 

Hear insights and views from our leading line up of industry experts:
Bruno Flamion, Chair, CHMP Scientific Advice Working Party, EMA
Nicholas Dracopoli, Vice President, Biomarkers, Centocor Research & Development, Johnson & Johnson
Mark Jones, Director Experimental Medicine (Biomarkers), New Medicines, UCB New Medicines
Stewart Bates, Director Biomarker Discovery, Biopharm R&D, GlaxoSmithKline
Chris Chamberlain, Medical Director Personalised Medicine, AstraZeneca
Vicki Ikin, Clinical Biomarker Scientist Group Manager, AstraZeneca
Gabriel Vargas, Biomarker Expert & Head of the CNS Clinical Biomarker Group F.Hoffmann-La Roche
Stefan Scherer, Global Biomarker Head F. Hoffmann-La Roche / Genentech
Donna L. Mendrick, Director, Division of Systems Biology, National Center for Toxicological Research, Food and Drug Administration
Patricia Hurley, Head of Project Management and Biomarkers Division, ERA Consulting (UK) Ltd
Dinesh De Alwis, Senior Research Advisor, Group Leader Global PK/PD, Europe, Eli Lilly
Vicki Ikin, Clinical Biomarker Scientist Group Manager, AstraZeneca
Arndt Schmitz, Founding Scientist, Research Biobank, Bayer Schering Pharma AG
Debra Klatte, Director, Integrative Biology, Boehringer Ingelheim
Peter Smith, Senior Scientist II, Oncology, Millennium Pharmaceuticals
Birgitte Søgaard, Divisional Director, Clinical Pharmacology and Translational Medicine, Lundbeck
Maarten Van Roy, Associate Scientist, Pharmacology, Ablynx
Niroshan Ramachandran, Senior Manager, Research and Development, Life Technologies
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