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| 6th Annual Biomarkers Congress is administered by Osney Media. |
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Programme |
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6th Annual Biomarkers Congress 23rd & 24th February 2011
Wednesday 23rd February 2011 to Thursday 24th February 2011 The Hilton Deansgate Hotel, Manchester, UK, - £650.00/person

6th ANNUAL BIOMARKERS CONGRESS: the leading event for biomarkers practitioners
The pharmaceutical industry is facing high clinical development costs and declining drug discovery success rates. To stay competitive companies are re-evaluating their drug development process to reduce attrition rates. Biomarkers promises to transform drug discovery, clinical development and molecular diagnostics in the R&D process as effective use of biomarkers at each stage of R&D can improve decision-making, increase clinical trial success rates and productivity.
The 6th Annual Biomarkers Congress 2011 presented by Oxford Global Conferences provides a first class educational and networking opportunity for over 200 attendees to gain knowledge and insights into the Biomarkers marketplace.
The event explores core topics such as discovery & validation strategies, regulatory issues, the key role of personalised medicine and diagnostics, safety biomarkers and biomarkers within clinical development, as well as the integration of applications and enabling technologies such as genomics, microRNA, systems biology to maximise biomarker identification.
Do not miss out on the opportunity to learn how you can streamline your R&D process and identify potential cost savings through successful biomarker discovery, validation and clinical development. Focus on the integration of technologies & applications to bridge the gap between Discovery, Validation and Development.
CONFERENCE AGENDA
STREAM TITLES
· Biomarker Discovery & Validation Strategies & Regulation
· Companion Diagnostics & Stratified Medicine
· Safety & Biomarkers in Clinical Development
· Enabling Technologies to Maximise Biomarker Identification
· Oncology Biomarkers
Day One
Keynote Presentations
From Representatives from FDA and EMA
Stream One Biomarker Discovery & Validation Strategies & Regulation
Regulatory Issues
Validation
IMI Update
Outsourcing Models
Pharmacoeconomics of Biomarkers
Level of Characterisation of Biomarkers Required For Internal Go / No Go Key Investment Decision Making
Stream Two Companion Diagnostics & Stratified Medicine
Development of Companion Diagnostics including Novel Therapies
Understanding Regulatory aspects Concerning Companion Diagnostics
Case Study Examples
Development Through Predictive v Retrospective Biomarker Analysis
Statistical Issues and Stratified medicine
Challenges in Developing A Clinically Validated Companion Diagnostic
FDA Guidance
Day Two
Stream One Safety & Biomarkers in Clinical Development
Safe-T Consortium Case Study
Safety Biomarker Case Studies
Use of Safety Biomarkers for Guided Drug Development
Use of Predictive Animal Models
Translating Clinical Biomarkers into Clinical Decisions
Developing Molecular Biomarkers to Replace Traditional Clinical Endpoints
Stream Two Enabling Technologies to Maximise Biomarker Identification
Systems Biology Approaches to Inform Clinical Studies
Circulating Messenger RNA
MicroRNA
Epigenetics / DNA Methalytion
Pharmacogenetics
NGS
Multiplexing Technology
Biobanking as an Enabling Technology for Biomarker Research
Oncology Biomarkers Congress (Day 1 and 2)
Challenges in Oncology Drug Development
K-RAS Success Story
Oncology Biomarker Case Studies by Disease Area
Diagnostics v Pharmacodynamics
Exploring PK/PD Interactions and Applications
Use Of PK/PD Modelling Approaches to Impact Oncology Drug Development
Utilizing Biomarkers to Support Targeted therapies in Oncology
Use of gene Expression to Deliver Approaches Personalised Cancer Therapy
Selecting the Right Biomarker in Oncology Patients
Patient Selection
Circulating Tumour Cells
Translating In Vitro and Lab findings into Clinical Applications
Roundtable Discussions
CNS
Respiratory
Cardiovascular, Metabolic and Endocrine Diseases
Oncology
Inflammation
Neurology
The conference this year will be co-located with the inaugural Oncology Biomarkers Congress which will also last two days and will give the opportunity to drill down into this particular therapeutic area.
The Conference Agenda has been shaped by research with an expert advisory panel:
Advisory Panel IncludeS:
· Francis Kalush, Network Leader for the Diagnostics (In vivo and In Vitro) and Personalized Medicine Network, FDA
· Alain van Gool, Head Molecular Profiling, Translational Medicine Research Centre, Merck Research Laboratories, MSD, Singapore
· Neil French, Senior Scientific Operations Manager, MRC Centre for Drug Safety Science, Department of Pharmacology & Therapeutics, The University of Liverpool
· Mark Jones, Associate Director Molecular Biomarkers, Global Exploratory Development, UCB New Medicines
· Miro Venturi, Senior Biomarker & Experimental Medicine Leader, Roche Pharma Development
· Mike Lau, Principal Clinical Development Scientist, GSK Oncology
· Gary Coulton, Director St. George's Medical Biomics Centre, St. George', University of London
· Chris Chamberlain, Medical Director Personalised Medicine, AstraZeneca
· Steve Furlong, Safety Science Lead and Senior Director, AstraZeneca
· Samila Mihindukulasuriya, Senior. Contract Analyst, Biomarkers, GSK
· Iain Kilty, Director Allergy & Respiratory Research Unit, Pfizer
· Matt Squires, Associate Director Translational Biology, Astex Therapeutics
· Ian Wilson, Senior Principal Scientist, Dept. of Drug Metabolism and Pharmacokinetics, AstraZeneca
· Patricia Hurley, Head of Project Management and Biomarkers Division, ERA Consulting (UK) Ltd
· Samual Murray, President, Greek Society of Molecular Oncology (ElEMO), Professor University of Ioannina Cancer Biobank
· Michael Shi, Director and Biomarker Project Leader of Exploratory Oncology Development, Novartis
· Simon Westbrook, Head of in Vivo Pharmacology, Biomarkers, Pfizer
· Dominic Eisinger, Director of Strategic Development, Rules-Based Medicine, Inc
· Michael Shi, Director and Biomarker Project Leader of Exploratory Oncology Development, Novartis
· Simon Westbrook, Head of in Vivo Pharmacology, Biomarkers, Pfizer
· Dominic Eisinger, Director of Strategic Development, Rules-Based Medicine, Inc
Delegates will benefit from:
- An executive format providing intimate interaction with industry peers’ ideas and experiences through case study presentations and panel discussions
- Networking opportunities and sharing ideas with other senior biomarker practitioners
- Pre-scheduled one-to-one meetings between you and solution providers will provide you with an opportunity to forge partnerships and discover solutions
- Post event follow up offering all documentation from the meeting and re-booking discounts
- Tailor-made agenda – hand pick any conference and panel sessions you wish to attend
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| Hear insights and views from our leading line up of industry experts: |
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Bruno Flamion, Chair, CHMP Scientific Advice Working Party, EMA
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Nicholas Dracopoli, Vice President, Biomarkers, Centocor Research & Development, Johnson & Johnson
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Mark Jones, Director Experimental Medicine (Biomarkers), New Medicines, UCB New Medicines
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Stewart Bates, Director Biomarker Discovery, Biopharm R&D, GlaxoSmithKline
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Chris Chamberlain, Medical Director Personalised Medicine, AstraZeneca
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Vicki Ikin, Clinical Biomarker Scientist Group Manager, AstraZeneca
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Gabriel Vargas, Biomarker Expert & Head of the CNS Clinical Biomarker Group F.Hoffmann-La Roche
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Stefan Scherer, Global Biomarker Head F. Hoffmann-La Roche / Genentech
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Donna L. Mendrick, Director, Division of Systems Biology, National Center for Toxicological Research, Food and Drug Administration
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Patricia Hurley, Head of Project Management and Biomarkers Division, ERA Consulting (UK) Ltd
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Dinesh De Alwis, Senior Research Advisor, Group Leader Global PK/PD, Europe, Eli Lilly
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Vicki Ikin, Clinical Biomarker Scientist Group Manager, AstraZeneca
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Arndt Schmitz, Founding Scientist, Research Biobank, Bayer Schering Pharma AG
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Debra Klatte, Director, Integrative Biology, Boehringer Ingelheim
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Peter Smith, Senior Scientist II, Oncology, Millennium Pharmaceuticals
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Birgitte Søgaard, Divisional Director, Clinical Pharmacology and Translational Medicine, Lundbeck
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Maarten Van Roy, Associate Scientist, Pharmacology, Ablynx
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Niroshan Ramachandran, Senior Manager, Research and Development, Life Technologies
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